3D Cell Culture Tools

InSphero's 3D cell culture plates and platforms support reproducible spheroid and organoid workflows, from model formation and long-term culture to imaging, screening, and automation. Explore Akura™ 96- and 384-well ultra-low attachment microplates for scaffold-free 3D culture, Gri3D® hydrogel microcavity plates for standardized spheroid and organoid generation, and advanced organ-on-chip platforms when your study requires physiological flow to study organ-organ interactions. Compare our 3D cell culture plate formats below to find the technology that best fits your model and workflow.

Akura™ Ultra-Low Attachment Microplates

Akura™ Spheroid Microplates are 3D cell culture plates designed for reproducible scaffold-free spheroid and organoid formation, culture, treatment, and analysis.
Available in 96- and 384-well formats, these ultra-low-attachment microplates support workflows from routine 3D assay development to high-throughput screening, with compatibility for medium exchange, imaging, and automated handling.

Akura™ 96 Spheroid Microplate

Akura™ 384 Spheroid Microplate

Akura™ PLUS Hanging Drop System

Gri3D® Hydrogel Microcavity Plates

Gri3D® Plates are designed to provide precise, scalable, and reproducible 3D cell culture in a single focal plate. Each plate contains a high-density array of hydrogel microcavities that support the uniform formation of organoids, enabling researchers to generate hundreds of organoids in one well, ideal for image-based endpoints at the single organoid level with high statistical power.

The plates are compatible with automated liquid handling and imaging systems, simplifying workflows from early discovery to high-throughput screening. Gri3D® Plates can be applied across various research areas, including toxicology, cancer biology, drug development, and tissue engineering, to support consistent and reliable experimental outcomes. 

Beyond 3D Cell Culture Plates: Akura™ Organ-on-Chip Platforms

If you would like to augment your 3D assay and add physiological flow, organ-organ interaction, and immune competence, we propose one of our Advanced Organ-on-Chip Platforms. Built on the Akura™ Spheroid Microplates and Models, you can easily transfer all established readouts while preserving the high robustness, reliability, and scalability.

3D Cell Culture Tools: Accessories

Upgrade your in vitro experiments with innovative solutions for a reliable 3D cell culture experience. Please find below essential accessories for your 3D cell culture success. 

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