3D Cell Culture Tools
For more than a decade, InSphero has developed and optimized technologies for robust and reproducible production, cultivation and assaying of 3D spheroids and organoids. In countless successful collaboration projects with pharmaceutical and biotech partners, our technology has contributed to deep biological insights, better decisions and safer drugs.
Leverage the most complete portfolio of 3D Plate formats and accessories for 3D cell culture.
Akura™ Ultra-Low Attachment Microplates
Microplates are an essential tool in scientific research, widely used for cell culture, drug discovery, and biochemical assays. They enable researchers to perform multiple experiments in parallel, significantly improving efficiency and throughput. Among the most common formats are 96-well and 384-well plates. Ultra-Low Attachment (ULA) plates feature a specialized surface coating that prevents cell adhesion, making them particularly suitable for scaffold-free 3D in vitro models.
Akura™ 3D Cell-Culture Tools
Gri3D® Hydrogel Microcavity Plates
Gri3D® Plates are designed to provide precise, scalable, and reproducible 3D cell culture in a single focal plate. Each plate contains a high-density array of hydrogel microwells that support the uniform formation of organoids, enabling researchers to generate hundreds of organoids in one well, ideal for image-based endpoints at the single organoid level with high statistical power.
The plates are compatible with automated liquid handling and imaging systems, simplifying workflows from early discovery to high-throughput screening. Gri3D® Plates can be applied across various research areas, including toxicology, cancer biology, drug development, and tissue engineering, to support consistent and reliable experimental outcomes.
Akura™ Organ-on-Chip Platforms
If you would like to augment your 3D assay and add physiological flow, organ-organ interaction, and immune competence, we propose one of our Advanced Organ-on-Chip Platforms. Built on the Akura™ Spheroid Microplates and Models, you can easily transfer all established readouts while preserving the high robustness, reliability, and scalability.
Advanced 3D Cell Culture Tools with Physiological Flow
3D Cell Culture Tools: Accessories
Upgrade your in vitro experiments with innovative solutions for a reliable 3D cell culture experience.


















