

Akura™ 384 ImagePro
The Akura™ ImagePro is our high-end solution plate that unifies robust liquid and spheroid handling with automated high-resolution imaging. The flat bottom and black walls of the 384 well plate facilitate high-resolution, high-content imaging, while the special well design allows medium exchange, dosing, and endpoint determination in the same plate saving time and resources.
- All-in-one plate allowing spheroid formation, long-term culturing and analysis in one single plate
- Unique SureXchange™ ledge engineered to prevent unintended spheroid/organoid aspiration and to retain consistent minimal remnant media volumes (< 2-3 µl) during medium exchange
- Spheroid/organoid morphology and functionality are preserved in long-term culture
- Superior high-content imaging quality with a continuous, flat-bottom, 25 μm gas-permeable membrane, and a black-walled body


Architecture
Handling
High Content Imaging
Architecture
- The unique well design with SureXchange™ ledge protects the spheroid from aspiration while leaving a minimal residual volume (2-3 μl)
- ANSI/SLAS standard format for full compatibility with automated liquid handling and high-content imaging systems
- A two-component plate consisting of a black polystyrene body and a 25 μm, continuous gas-permeable FEP membrane
Handling
- >90% medium removal without spheroid loss using manual or automated pipetting
- Ultra-low attachment surface with a stable cell-repellent coating
- Biologically inert, and non-degradable surface compatible with cell culture and in-plate post-culture processing steps such as cell lysis and fixation procedures
High Content Imaging
- Continuous flat bottom with excellent planarity for imaging applications with immersion objectives, minimal optical aberration, and constant spheroid z-position
- Ultra-thin bottom improving imaging z-depth and resolution by minimizing light scatter
- The black-walled body eliminates fluorescent crosstalk between wells
- Defined 1-mm quick-reference region of interest for increased imaging speed
Compare Akura™ 384 ImagePro and Akura™ 384 Spheroid Microplate
- Both Akura™ 384 Plates have black walls to minimize cross-talk and a unique well design for near-complete medium exchange without spheroid loss.
- The Akura™ 384 ImagePro has a flat, ultrathin, 25 µm gas-permeable membrane made of FEP (fluorinated ethylene propylene) to minimize RI mismatch and it is compatible with high NA objectives.
- The Akura™ 384 Spheroid Microplate has a 125 µm thin Polystyrene membrane. The plate is especially suited for high throughput applications, lytic and biochemical assays, and basic confocal imaging endpoints.
If your main focus is on biochemical assays and basic imaging, we recommend the Akura™ 384 Spheroid Microplate.
Product Documents
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