Akura™ 384 Spheroid Microplate

High throughput screening with robust automation

Akura™ 384 Spheroid Microplate

The Akura™ 384 Spheroid Microplate is our ultimate spheroid screening plate unifying robust liquid and spheroid handling with automated high-throughput screening applications. The flat bottom and black walls of the InSphero 384-well plate facilitate fluorescent imaging, while the special well design allows medium exchange, dosing, and endpoint determination in the same plate saving time and resources.

  • All-in-one plate allowing spheroid formation, long-term culturing and analysis in one single plate
  • Unique SureXchange™ ledge engineered to prevent unintended spheroid/organoid aspiration and to retain consistent minimal residual volume (2-3 µl) during medium exchange
  • Spheroid/organoid morphology and functionality are preserved in long-term cell culture
  • Superior fluorescent imaging quality with a continuous, flat-bottom, 125 μm Polystyrene membrane, and a black-walled body


Compare Akura™ 384 Spheroid Microplate and Akura™ 384 ImagePro

  • Both Akura™ 384 Plates have black walls to minimize cross-talk and a unique well design for near-complete medium exchange without spheroid loss.
  • The Akura™ 384 Spheroid Microplate has a 125 µm thin Polystyrene membrane. The plate is especially suited for high throughput applications, lytic and biochemical assays, and basic confocal imaging endpoints.
  • The Akura™ 384 ImagePro has a flat, ultrathin, 25 µm gas-permeable membrane made of FEP (fluorinated ethylene propylene) to minimize RI mismatch and it is compatible with high NA objectives.

If you require a high-resolution, high-content imaging endpoint, we recommend the Akura™ 384 ImagePro Plate.

Product Documents

Scalable 3D Cell Culture Technologies Engineered for Physiological InSight

Semi-automated medium exchange in Akura™ 96 and 384 Microplates with INTEGRA VIAFLO

Three practical steps to transform 3D cell culture

InSphero Portfolio of 3D Microplate Formats

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