Innovation through collaboration
InSphero works closely with leading technology providers and academic collaborators to develop 3D cell-based assay applications, helping our customers to extract the most useful data from 3D InSight™ Microtissues using the latest gold-standard detection and imaging technologies. Many of these applications are available to customers as certified Technical Protocols, or are available through our portfolio of 3D InSight™ Services.
Perkin Elmer Corp.
PerkinElmer partners with InSphero in development of functional imaging of 3D microtissues using the Opera Phenix™ High-Content Screening System and Operetta® High–Content Imaging System for advanced toxicology and efficacy testing applications. PerkinElmer is also the exclusive world-wide distributor of InSphero hanging-drop and ULA 3D cell culture plates.
Promega Corp., USA
One of the world’s most trusted providers of luminescent and fluorescent-based assay providers, Promega has worked closely with InSphero since 2010 to validate and optimize assays for use with 3D microtissues, including CellTiter-Glo® ATP assays, LDH and apoptosis assays, as well as high-quality RNA extraction from InSphero microtissues.
Biognosys AG, Switzerland
Biognosys is a leading proteomics company, providing superior technology and software for highly multiplexed protein quantification. Biognosys has partnered closely with InSphero to provide high-sensitivity and specificity proteomics analysis to characterize 3D InSight™ Microtissue functionality, and provide ground-breaking insights in toxicity and efficacy omics applications.
Seahorse Bioscience, Inc., USA (Agilent Technologies)
The Seahorse platform from Agilent Technologies is the gold-standard portfolio of metabolic analyzers and assay kits for measuring real-time cell metabolism in live cells. Seahorse and InSphero have worked closely to optimize protocols using the XFe96 Spheroid Microplate to enable functional, metabolic measurements of 3D InSight™ Microtissues via innovative microplate geometry that ensures correct positioning of the spheroid to deliver reproducible measurements of cellular respiration and glycolysis. Related service: 3D InSight™ Mitochondrial Toxicity Testing in Human Liver Microtissues.
ALPCO is a trusted manufacturer of testing solutions used by scientists and healthcare professionals to advance research and quality of care. The STELLUX® portfolio of chemiluminescent biomarker ELISA kits provides the sensitivity and wide dynamic range required to efficiently and reliably detect key analytes released from microtissues, such as insulin released from 3D InSight™ Human Islet Microtissues.
ETH Zurich, Switzerland
Prof. Dr. Andreas Hierlemann, Bio Engineering Laboratory Basel
Goethe University Frankfurt, Germany
Prof. Dr. Ernst Stelzer, Institute of Cell Biology and Neuroscience
Helmholtz Zentrum München, Germany
Prof. Dr. Michael J. Atkinson, Institute of Radiation Biology
Leibniz Research Center for Working Environment and Human Factors, Germany
Prof. Jan Hengstler, director of IfaDo
Medical University of Innsbruck, Austria
Dr. Arno Ammann, Laboratory for Molecular Cell Biology
Prof. Dr. Alain G. Zeimet, Department of Obstetrics and Gynecology
University of Berne, Switzerland
Dr. Christian Zuppinger, Department of Clinical Research, Cardiovascular Research Group