Islet Applications - Diabetes | InSphero

3D InSight™ Islet Microtissues are uniform, functionally robust, and long-lived primary islets. These islets are designed for the high-throughput study of pancreatic islet function, regeneration, and preservation.

The uniform size, cellular composition, and functionality of our islet microtissues minimize intra-assay and intra-donor variability associated with native islets. Furthermore, improved viability in culture enables the assessment of long-term compound effects and disease modeling.

Islet Applications

β-cell function and insulin secretagogues

α-cell function and
glucagon suppressors

Islet viability and apoptosis

β-cell proliferation

Type 1 & Type 2 diabetes

Dynamic insulin secretion

Drug-induced pancreatic endocrine injury

InSphero Solutions

Microtissue Models


Request Additional Resources

Brochure: Islet Microtissues


3D InSight™ Islets White Paper


Find out how you can accelerate

your diabetes drug discovery

Get Started