Liver Applications - Fibrosis & NASH | InSphero

3D InSight™ Liver Disease models are based on 3D InSight™ Human Liver Microtissue technology.  They are engineered to incorporate all the primary human liver cells required to recapitulate the disease state, including primary hepatocytes, Kupffer cells, hepatic stellate cells, and liver endothelial cells.  These advanced models are designed for high throughput screening and efficacy testing of drugs for metabolic diseases of the liver, such as diet-induced steatosis, NASH, and liver fibrosis, and are ideal for long-term dosing protocols necessary to gauge effectiveness of novel compounds. Watch this video to learn how we developed the first preclinical in vitro model for NASH and fibrosis.

Liver Applications

Human Liver Spheroid model for toxicology testing

Diet-induced Steatosis

Extend your assay window for efficacy testing of anti-steatotic drugs

Human Liver Spheroid model for toxicology testing

NASH

Test efficacy of anti-NASH drugs in an advanced 3D liver disease model

Human Liver Spheroid model for toxicology testing

Liver Fibrosis

Test efficacy of anti-fibrotic drugs in an advanced 3D liver disease model

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Brochure: FFA-BSA Kit for steatosis induction

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Human Liver in vitro NASH Model

Brochure: NASH Model

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Brochure: Human Liver Fibrosis Model

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