3D InSight™ Tumor Microtissues are an ideal tool for drug discovery, owing to their 3-dimensional spheroidal shape, tumor and stromal-cell-type components, and native-like extracellular matrix (ECM) protein composition. They are a proven, robust method for assessing penetration of antibodies and engineered antibody fragments in vitro (1,2). They can also be used for assessing effectiveness of therapeutics designed to prevent tumor relapse.

1. Sha H et al. J Control Release. 2015 Feb 28;200:188-200.
2. Thurber GM and Wittrup KD Cancer Res. 2008 May 1;68(9):3334-3334.