3D Cell-based technology Archives - InSphero
September 28, 2018

Understanding Microfluidics: the Technology Behind Body-on-a-Chip Systems

Microfluidic chips enable researchers to manipulate, image, and analyze small tissue constructs under optimal culturing conditions. Microfluidics, the technology behind emerging #body-on-a-chip and #organs-on-chips systems, is poised to transform the […]
August 20, 2018

Can 3D in vitro models deliver what pharma needs for NASH and Fibrosis drug discovery?

Pharma companies racing to develop new drugs to combat chronic liver diseases, such as NASH and fibrosis, need better preclinical testing tools for compound screening and mechanistic studies. Here’s how […]
July 18, 2018

Reaggregated human islets: the next gold standard in vitro model for diabetes research?

Correlating human pancreas donor characteristics with 3D InSight™ Islet Microtissue functionality confirms reaggregated islets are a robust, physiologically relevant model for diabetes research. With diabetes approaching epidemic proportions globally, there […]
June 29, 2018

Building a Better Model to Detect Mitochondrial Liabilities

InSphero and Agilent discuss the need for metabolically competent models with stable metabolic activity for mitochondrial toxicity testing in a new textbook chapter. Mitochondrial Dysfunction Caused by Drugs and Environmental […]
June 18, 2018

Why we need better preclinical models for NASH Drug Discovery

In honor of the inaugural International NASH Day, an initiative to raise awareness of nonalcoholic steatohepatitis (NASH), I thought it would be appropriate to reflect on the current status of […]
May 29, 2018

AstraZeneca and Genentech publish comprehensive evaluation of 3D spheroid hepatic cultures

Landmark study comparing 2D and 3D DILI models shows 3D InSight™ Human Liver Microtissues are a highly predictive liver toxicology model that outperforms 2D primary human hepatocytes in culture. In […]
May 28, 2018

InSphero Akura™ Flow: Transforming Drug Discovery and Development with Body-on-a-Chip Technology

InSphero Akura™ Flow body-on-a-chip technology may help make animal testing in pharma and cosmetic companies obsolete How can we better predict how new drugs act in the human body? This […]