Liver Toxicology Archives - InSphero
August 20, 2018

Can 3D in vitro models deliver what pharma needs for NASH and Fibrosis drug discovery?

Pharma companies racing to develop new drugs to combat chronic liver diseases, such as NASH and fibrosis, need better preclinical testing tools for compound screening and mechanistic studies. Here’s how […]
June 29, 2018

Building a Better Model to Detect Mitochondrial Liabilities

InSphero and Agilent discuss the need for metabolically competent models with stable metabolic activity for mitochondrial toxicity testing in a new textbook chapter. Mitochondrial Dysfunction Caused by Drugs and Environmental […]
May 29, 2018

AstraZeneca and Genentech publish comprehensive evaluation of 3D spheroid hepatic cultures

Landmark study comparing 2D and 3D DILI models shows 3D InSight™ Human Liver Microtissues are a highly predictive liver toxicology model that outperforms 2D primary human hepatocytes in culture. In […]