20 - 24.08.2017 - 10th World Congress - Alternatives and Animal Use in the Life Sciences

 

Discover the 3Rs of InSphero 3D InSight™ Microtissue Platforms

Relevance. Robustness. Reproducibility.

Visit InSphero at the 10th World Congress in Seattle to learn how our advanced 3D microtissues are raising the bar with physiologically relevant in vitro models that can help reduce the use of in vivo animal studies in drug discovery and development.  

  • Relevant – using primary human-derived cells, our liver, islet and tumor models enables in vitro efficacy and safety studies that are more predictive of the in vivo response in humans
  • Robust – culturing primary cells in a scaffold-free 3D format results in more in vivo-like tissue structure and functionality, and extends the in vitro longevity of the model, allowing for long-term, repeat dose drug exposure studies
  • Reproducible – our 3D Select™ Process and patented 96-well assay platform ensure unrivaled physiological robustness, with the consistency and automation-friendly assay formats to meet industry-scale screening demands 

 

Raising the bar for improved physiological relevance

Achieve DILI prediction with 2X the sensitivity of 2D PHH assays

AZ Gen Paper thumb 01AstraZeneca and Genentech put 3D InSight™ Human Liver Microtissues to the test against 110 clinically defined DILI compounds. Read the summary of the landmark Archives of Toxicology 2017 paper and download it for your summer science reading list.

 

 

  

Investigate mechanisms of toxicity with our new in vitro 3D monkey liver model

3D InSight Monkey Liver MicrotissuesNow you can translate and troubleshoot hepatotoxicity detected in in vivo cynomolgus monkey studies using an in vitro 3D monkey liver model.  3D InSight™ Monkey Liver Microtissues are an organotypic co-culture of primary cynomolgus hepatocytes retaining the advanced, integrated biology required for species-specific studies in investigative toxicology. Visit booth 407 to learn more! 

   

 

Accelerate diabetes drug discovery with standardized pancreatic islet microtissues

3D InSight™ Islet Microtissues are uniform, functionally robust, and long-lived primary islets delivered pre-qualified and assay-ready for studying islet function, regeneration and preservation.  Gain 13-fold glucose-responsive insulin secretion in a highly reproducible primary human model that eliminates tedious hand-picking!  View our islet poster presentation.

 

Your 3D InSight™ Conference Planner

Conference Dates
August 20-24, 2017

Venue
Washington State Convention Center, Seattle, WA  USA


Booth
407

View the 10th WC Online Program

  Oral Presentations

Exhibitor Hosted Session

Thursday, August 24, 10:00 - 10:15 AM, Room 608 (Program Number III-4-191)
In vitro skin microtissue model for toxicology and efficacy testing

Product Manager Simon Strobel

Presented by Dr. Simon Ströbel, InSphero AG

 

Poster Presentations

sot2017poster

Time TBD
Abstract 230: GravityFLOW: A Microtissue-based Multi-tissue Platform
Presented by Dr. Lei He

InSphero xspecies Posters at SOT 2017

Time TBD
Abstract 339: A robust In Vitro Islet Model: Long-lived, Standardized, and Glucose-responsive Human Islet Microtissues
Presented by Dr. Sue Grepper

Company video

company-video-inspheor