ADA 78th Scientific Sessions 2018 - InSphero

ADA 78th Scientific Sessions 2018

Jun 22 - 26, 2018

Diabetes Breakthroughs Happen with 3D InSight™

jump to section

Meet the InSphero team at the American Diabetes Association 2018 meeting to learn how you can take full advantage of our 3D InSight™ Diabetes Discovery Platform.

Tailored Solutions for Research

Take advantage of our

high-throughput compatible scalable 3D Technology

Schedule a Meeting

Robust Islet Models Expert Assay Services

human islet spheroid model for diabetes and islet research

Uniform 3D InSight™ Microtissues

for reproducible results

Advanced Disease Modeling

Certified Applications

      • β-cell function
      • β-cell proliferation
      • α-cell function
      • Islet viability and apoptosis

Reliable Assessment of β-cell Function

Talk to our team at ADA to learn about our new partnership with ALPCO and our comprehensive β-cell function application suite that includes everything you need to quantify insulin secretion from 3D InSight™ Islet Microtissues.

    • Use a robust and standardized primary islet model in high-throughput and longitudinal studies of β-cell function, regeneration and preservation
    • Achieve robust and accurate quantification of insulin secretion from 3D InSight™ Islet Microtissues with the high sensitivity and broad dynamic range of ALPCO STELLUX® ELISAs
    • Save time and ensure reliable, reproducible results by ordering media, buffers, and endpoint assays certified for use with 3D InSight™ Islet Microtissues
jump to section

Conference Details

jump to section
jump to section

In-Booth Poster Presentations

The following posters will be on display at InSphero Booth 1567, during exhibition hours, June 23 – 25.

Disease Modeling

Physiologically Relevant Disease Modeling with 3D InSight™ Human Islet Microtissues
Contributing Authors: Aparna Neelakandhan1, Adelinn Biernath1, Felix Forschler1, Joan Mir, Burcak Yesildag1; 1 InSphero AG, Schlieren, Switzerland

Insulin Release Dynamics

Using Uniform Reaggregated Pancreatic Islets in a Microfluidic Perifusion System Enables Studying Insulin Release Dynamics at Single-Islet Level (in collaboration with ETH Zürich)
Contributing Authors: Burcak Yesildag1, Patrick M. Misun2, Felix Forschler2, Aparna Neelakandhan1, Adelinn Biernath1, Andreas Hierlemann2, Olivier Frey1; 1 InSphero AG, Schlieren, Switzerland; 2 ETH Zürich, Dept. of Biosystems Science and Engineering, Bio Engineering Laboratory, Basel, Switzerland

β-Cell Proliferation

A Novel Standardized In Vitro Model System for Assessment of Pancreatic β-Cell Proliferation
Contributing Authors: Burcak Yesildag1, Eva-Marie Andersson2, Aparna Neelakandhan1, Adelinn Biernath1, Laurent Knerr2, Henrik Gradén2, Carina Ämmälä2; 1InSphero AG, Schlieren, Switzerland, 2AstraZeneca, Cardiovascular and Metabolic Diseases, Innovative Medicines and Early Development Biotech Unit – Mölndal, Sweden

Pancreatic Islets on a Chip

Akura™ Flow: A Microfluidic Multi-Tissue Platform Engineered for 3D InSight™ Microtissues
Contributing Authors: Fabrizio Hürlimann¹, Christian Lohasz², Burçak Yesildag¹, David Fluri¹, Kasper Renggli², Andreas Hierlemann², Olivier Frey¹; ¹InSphero AG, Schlieren, Switzerland; ²ETH Zürich, Department of Biosystems Science and Engineering, Basel, Switzerland