DECHEMA 3D Cell Culture 2018 - Insphero

DECHEMA 3D Cell Culture 2018

Jun 05 - 07, 2018

Discover the Next Generation of Body-on-a-Chip Technology

Meet InSphero Head of Technology Platforms Dr. Olivier Frey at DECHEMA 3D Cell Culture to learn about ongoing efforts and various applications of tissues-on-chips technology.  Dr. Frey will be available during the conference to discuss how InSphero can help you:

  • Use the latest technology to test drugs on organ models to better understand how they may affect the body as a whole
  • Address common challenges of emerging microfluidic devices with the InSphero Akura™ Flow microphysiological system.
  • Become an application development partner and help shape the future of Organs- and Tissues-on-Chips in drug discovery and development

Schedule a Meeting

Akura Flow™ for Integrated Organs-on-Chips

Together with our collaborators at Roche and ETH Zürich, we will present how Akura™ Flow, our new microphysiological system, designed for organs-on-chips applications  using multiple types of 3D InSight™ microtissues, and can be used to:

  • Minimize cell, medium and compound use in a miniaturized 10-microtissue configuration
  • Leverage maximum physiological complexity while minimizing operational complexity
  • Compare numerous conditions in parallel on one plate in a scalable, automation-compatible platform
  • Employ a diverse array of experimental endpoints

Conference Detail

  • Conference Dates: June 5-7, 2018

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Oral Presentations

From Models to High Throughput

Wednesday, June 6, 3:40 – 4 PM
Microtissues meet microfluidics – next generation microphysiological tilting system
Presenting Author: K. Renggli, PhD, ETH Zürich
Contributing Authors:C. Lohasz¹; S. Bürgel¹; D. Fluri²; A. Hierlemann¹; O. Frey²
¹ ETH Zürich, Basel/CH; ² Insphero AG, Schlieren/CH

Safety and Toxicity Testing

Thursday, June 7, 12 – 12:20 PM
A Novel 3D Human Liver Fibrosis Model for ntifibrotic Drug Discovery
Presenting Author: Patrick Guye, PhD, InSphero
Contributing Authors: P. Guye¹, S. Messner¹; ¹ Insphero AG, Schlieren, CH

Thursday, June 7, 12:40 – 1 PM
Microfluidic Platform for Advanced Embryotoxicity Testing in vitro
Presenting Author: J. Boos, PhD, ETH Zürich
Contributing Authors:J. Boos¹; A. Michlmayr¹; K. Renggli¹; O. Frey²; A. Hierlemann³; ¹ ETH Zürich, D-BSSE Basel, Basel/CH; ² Insphero AG, Schlieren/CH; ³ ETH Zürich, D-BSSE Basel, Basel/CH

Poster Presentations

Complex and Multi-Cell Type Models

Poster 1.3.02
Towards a three-dimensional microfluidic in vitro model to assess efficacy & safety of immune-stimulatory antibody drugs
Presenting Author: R. Nudischer, F. Hoffmann-La Roche Ltd.
Contributing Authors: C. Bertinetti-Lapatki²; C. Claus³; K. Renggli⁴; C. Lohasz⁴; O. Frey⁵; A. Hierlemann⁴; A. Roth²; ¹ F. Hoffmann-La Roche Ltd., Basel/CH; ² Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel/CH; ³ Roche Pharma Research and Early Development, Roche Innovation Center Zürich, Schlieren/CH; ⁴ ETH Zürich, D-BSSE Basel, Basel/CH; ⁵ Insphero AG, Schlieren/CH

Poster 1.3.12
Development and characterization of PDX-derived 3D tumor microtissues as platform for screening targeted molecular therapeutics
Presenting Author: N. Buschmann, Insphero AG, Schlieren/CH
Contributing Authors: F. Chiovaro¹; N. Buschmann²; I. Agarkova²; A. Maier³; S. Messner²; J. Schueler³; P. Guye²; ¹ InSphero AG, Schlieren/CH; ² Insphero AG, Schlieren/CH; ³ Charles River, Freiburg im Breisgau/D

Translation of Models to Solutions

Poster 2.1.02
Microphysiological system based on human liver microtissues for intrinsic clearance prediction
Presenting Author: F. Hürlimann, InSphero AG
Contributing Authors: S. Mannino²; C. Lohasz³; K. Renggli³; A. Hierlemann³; L. Suter-Dick²; O. Frey¹; ¹ InSphero AG, Schlieren/CH; ² University of Applied Sciences and Arts Northwestern Switzerland, Muttenz/CH; ³ ETH Zürich, D-BSSE, Basel/CH

New Devices for 3D Cell Culture

Poster 3.3.07
A tubing-free, microfluidic tilting platform for the realization of in vivo-like drug exposure scenarios for three-dimensional microtissues
Presenting Author: C. Lohasz, ETH Zürich
Contributing Authors: O. Frey²; K. Renggli¹; A. Hierlemann¹; ¹ ETH Zürich, Basel/CH; ² Insphero AG, Schlieren/CH