3D InSight™ Human Islet Microtissues, Human Islet Model | InSphero

3D InSight™ Human Islet Microtissues are a standardized alternative to primary human pancreatic islets for reproducible, reliable, and more efficient research.

  • Expand your GSIS assay window and improve sensitivity to insulin secretagogues with a long-lived, robust model persisting more than 28 days in culture
  • Eliminate islet pooling and data normalization with islet microtissues homogeneous in size and cellular composition
  • Increase efficiency 6-fold by eliminating the need to hand pick islets with microtissues available bimonthly and delivered assay-ready in a non-adherent, 96-well plate
human islet spheroid model

Our uniform, functionally robust human islet model ensures reproducible results

Production of 3D InSight™ Islet Microtissues starts with fine-tuned dissociation of primary donor islets, followed by controlled scaffold-free cellular reassembly and maturation in customized media that support maximum survival and optimal metabolic functionality of highly sensitive primary islet cells. The resulting uniform islets provide minimal intra-assay and intra-donor variability, while sustaining robust and long-term function.

Characterization Data

Human Islet Microtissue Specifications

  • Guaranteed 28 days viability
  • 96-well format, 1 microtissue per well
  • Produced bimonthly, depending on islet donor availability

Order Information

Catalog # Description
MT-04-002-01 3D InSight™ Human Islet Microtissues
Media and Buffers*
CS-07-005-01 Human Islet Maintenance Medium, 500 mL
CS-07-005-02 Human Islet Maintenance Medium, 250 mL
CS-07-050-03 Human Islet Assay Medium, 125 mL
CS-07-051-01 Krebs-Ringer HEPES Buffer, 500 mL

* available only when purchased with 3D InSight™ Microtissues

Request Additional Resources

White Paper: An Advanced In Vitro Islet Model


Brochure: Islet Microtissues


Find out how you can accelerate diabetes drug discovery

with a robust islet model that ensures reproducible results.

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