Learn how to efficiently predict DILI with 3D InSight™ Human Liver Microtissues
Use our 3D InSight™ DILI Evaluation Kit to bring your bench scientists up to speed with new methods and prepare to adopt InSphero 3D microtissues as your standard preclinical model for DILI testing. This kit provides everything you need to evaluate 6 of your compounds alongside 6 reference compounds (for comparison and validation), including microtissues, pre-aliquoted reference compounds, optimized media, ATP assay reagents, and a detailed protocol. You get the full support of our 3D liver toxicology experts while you’re performing evaluation experiments, and in less than 3 weeks, you’ll have taken the first step toward integrating our microtissues into your DILI workflow.
Kit components and recommended DILI evaluation workflow
- 3D InSight™ Human Liver Microtissues (multi-donor hepatocytes, co-cultured with Kupffer cells) to test 6 of your compounds and 6 reference compounds
- Microtissue maintenance and specialized tox testing medium – optimized for use with our liver models
- 3D InSight™ Cytotoxicity Assay Kits, which use Promega CellTiter-Glo® technology
- 6 Reference compounds: Ambrisentan, Sitaxsentan, Tolcapone, Entacapone, Chlorpromazine, and Ketoconazole
|KT-02-121-14||3D InSight™ DILI Evaluation Kit. Includes:|