3D InSight™ Assay-ready Tumor Microtissues, Tumor Models | InSphero

Gain greater translational insights with pre-qualified tumor-stromal co-cultures

InSphero assay-ready 3D InSight™ Tumor Microtissues are designed to simplify and accelerate oncology drug efficacy testing. Using the 3D Select™ Process, our oncology experts have identified optimal culture conditions for large-scale, reproducible production of 3D spheroid models that better reflect complex tumor biology, enabling you to:

  • Leverage physiologically relevant 3D tumor co-cultures composed of tumor and stromal components for testing drugs and immunotherapeutics
  • Focus your bench time on experiments instead of model development and production by testing in fully QC’d, assay-ready 3D microtissues
  • Assess single agent or combinatorial efficacy of small molecules, biologicals, and ADCs using 3D optimized endpoints

Scaffold-free tumor-stromal co-cultures display cell-line and culture condition dependent cellular arrangements. In A549 and SKOV-3 co-culture models, fibroblasts (brown FAP staining) are integrated within the tumor cells. In the HCT-116 model, fibroblasts organize themselves in a central core that is surrounded by tumor cells.

Assay-Ready Tumor Microtissue Specifications

  • Viability model dependent
  • 96-well format, 1 MT/well
  • Produced on demand; production schedule dependent on cell line

Order Information

Tumor Microtissues (co-culture with NhDF)

Tumor TypeCell LineCatalog #
Lung
  • A549
  • Colo699
  • HCC-827
  • NCI-H2170
  • NCI-H1975
  • MT-01-007-03
  • MT-01-013-03
  • MT-01-027-03
  • MT-01-028-03
  • MT-01-030-03
Liver HepG2 MT-01-005-03
Colorectal
  • HCT-116
  • HT-29
  • MT-01-003-03
  • MT-01-004-03
Breast
  • MCF-7
  • MDA-MB-231
  • MDA-MB-361
  • MT-01-012-03
  • MT-01-026-03
  • MT-01-019-03
Ovarian SKOV-3 MT-01-031-03
Cervical C33-A MT-01-011-03
Kidney
  • A498
  • 786-0
  • MT-01-001-03
  • MT-01-021-03

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Brochure: Tumor Microtissues

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Poster: 3D InSight™ Oncology Drug Discovery Platform

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