3D InSight™ Custom Tumor Microtissues, Custom tumor Models | InSphero

Standardized tumor model development using the InSphero 3D Select™ Process

We can work with you to develop a custom tumor model to fit your project using our 3D Select™ Process and patented InSphero scaffold-free assay platforms. Select or provide a tumor cell line or PDX sample, and we’ll optimize conditions for microtissue formation to develop monoculture or co-culture (with fibroblasts) models to fit your needs. Once established, the model can be used in 3D InSight™ Oncology Services or delivered assay-ready for use in your lab.

Custom Tumor Model Specifications

Service Description

  • Feasibility and optimization of spheroid formation
  • Size-based growth kinetics over 10 days in culture
  • ATP after tissue formation and 10 days in culture
  • Histology at day 4 and 10 (H&E plus 3 markers)
  • Full written report and consultation
  • Model specifications

  • Viability model-dependent
  • 96-well format, 1 microtissue per well
  • Produced on demand; production schedule dependent on cell line or PDX material

Order Information

Supply your own cell line, or select from one of the many established tumor cell lines available for custom model development.

Tumor TypeCell LineFluorescence3D Monoculture
BreastMCF-7
TD-47D
MDA-MB-231
MDA-MB-361
MDA-MB-468
BT474

RFP
RFP
RFP

no
yes
no
yes
yes
yes
ColorectalDLD-1
LS174T
HCT-116
LoVo

GFP
GFP
yes
yes
yes
yes
StomachNCI-N87yes
LungA549
H292
NCI-H460
NCI-H2170
NCI-H1975
NCC-827
GFP




yes
yes
yes
yes
yes
yes
KidneyA498
786-O
COLO-205


yes
yes
no
Prostate22RV1
DU-145
LnCap
PC-3



yes
yes
yes
no
BrainSNB-19
NL-18

GFP
yes
yes
PancreasPANC-1no
OvarianA2780
SKOV-3
HEY


GFP
yes
no
yes
LiverHepG2yes
CervicalC33-Ano

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Brochure: Tumor Microtissues

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Poster: 3D InSight™ Oncology Drug Discovery Platform

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