3D InSight™ Cancer Drug Efficacy Testing Service | InSphero

Biochemical and phenotypic assessment of drug potency and efficacy

Accelerate and increase your chances of discovering more effective drugs using organotypic multicellular tumor microtissues. We’ll test your compounds or biologics of interest to evaluate their potency (EC50) and efficacy (maximum response) on tumor microtissues using 3D-optimized biochemical (viability) and phenotypic (size) endpoints.

  • Assess your test compounds in 3D InSight™ Tumor Microtissues (monoculture or co-culture)
  • Utilize a repeat-dosing regimen over 10 day exposure period with kinetic-size profiling (spheroid area) and viability endpoints
  • Receive potency (EC50) and efficacy (maximum response) values and growth curves for your compounds and two controls

Characterization Data

Service at a Glance

Download our brochure for details on the standard protocol.

Service Report includes

  • ATP-based dose-response curve
  • Size-based dose-response curve and growth kinetics over time
  • Potency (EC50) & efficacy (max response) values
Catalog #Description
SP-01-041-023D InSight™ Efficacy Testing Service
(any number of compounds, 2 controls, 1 model)

Request Additional Resources

Brochure: Oncology Services

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Poster: The 3D InSight™ Oncology Drug Discovery Platform

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Webinar: 3D Tumor Models for Drug Discovery

Find out how you can screen new cancer drugs more efficiently

with services using our advanced 3D tumor models.

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