Search for cures more efficiently with the 3D InSight™ Oncology Platform
InSphero 3D InSight™ Oncology Services for efficacy testing and immuno-oncology applications are designed to accelerate oncology drug discovery and help you gain greater translational insights. When you outsource tumor model development and preclinical testing of anti-cancer drugs and therapeutics to InSphero, we work with you to develop and implement a detailed study plan, and ensure you get robust, reliable results, and comprehensive reporting and analysis.
- Design a better model composed of the appropriate ratio of tumor cells, derived from cancer cell line or PDX material, and stromal cell components
- Test potency and efficacy of cancer drugs in a physiologically relevant model that better reflects the complex biology of tumor microenvironments
- Assess single agent or combinatorial efficacy of small molecule, biological, ADC or immunomodulatory drugs using 3D optimized endpoints
- Evaluate infiltration of immune cells or the effect of your drug on immune cell infiltration
Custom Tumor Model Development
Build a model with tumor and stromal components derived from cell line, PDX, or primary patient material.
Combinatorial Drug Testing
Test for synergistic effects of drug combinations in 3D InSight™ Tumor Microtissues.
Tumor Relapse Assay
Evaluate the potential for tumor recurrence following removal of drug.
Antibody Penetration
Optimize biological construct design by assessing antibody penetration into tumor microtissues.
Immuno-oncology
Evaluate immune cell infiltration, tumor cell killing, and immuno-therapeutic efficacy