Search for cures more efficiently with the 3D InSight™ Oncology Platform
InSphero 3D InSight™ Oncology Services for efficacy testing and immuno-oncology applications are designed to accelerate oncology drug discovery and help you gain greater translational insights. When you outsource tumor model development and preclinical testing of anti-cancer drugs and therapeutics to InSphero, we work with you to develop and implement a detailed study plan, and ensure you get robust, reliable results, and comprehensive reporting and analysis.
- Design a better model composed of the appropriate ratio of tumor cells, derived from cancer cell line or PDX material, and stromal cell components
- Test potency and efficacy of cancer drugs in a physiologically relevant model that better reflects the complex biology of tumor microenvironments
- Assess single agent or combinatorial efficacy of small molecule, biological, ADC or immunomodulatory drugs using 3D optimized endpoints
- Evaluate infiltration of immune cells or the effect of your drug on immune cell infiltration
Custom Tumor Model Development
Build a model with tumor and stromal components derived from cell line, PDX, or primary patient material.
Tumor Relapse Assay
Evaluate the potential for tumor recurrence following removal of drug.
Optimize biological construct design by assessing antibody penetration into tumor microtissues.
Evaluate immune cell infiltration, tumor cell killing, and immuno-therapeutic efficacy