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3D InSight™ | 3D In Vitro Liver Safety
Your proven end-to-end 3D in vitro liver safety solution portfolio - from reliable hazard identification to insights into translational and clinical toxicology
Industry-ready 3D In Vitro Liver Safety Solutions
InSphero’s 3D InSight™ Liver Safety solutions deliver precise and predictive 3D in vitro liver models for liver safety assessment since 2013. Our 3D in vitro liver safety technology accurately models the intricate architecture and functions of the human liver with a physiologically relevant microenvironment to enable better assessments of drug metabolism and toxicological responses. By incorporating our 3D InSight™ Liver Safety solutions into your workflow, you will gain valuable insights into:
Why 3D In Vitro Liver Safety with InSphero?
InSphero’s 3D In Vitro Liver Safety Platform has been developed with the needs of the safety toxicologists in mind: 3D in vitro human liver models with high biological and physiological relevance, short turn-around times, capable of handling larger compound sets when needed, and high reproducibility decision-enabling datasets.
Market-leading 3D in vitro biology you can rely on
The only 3D in vitro human liver model containing all liver cells, both parenchymal and non-parenchymal.
Trusted by pharmaceutical companies worldwide
Your team will value safety data backed by thousands of compound tests.
Comprehensive 3D In Vitro Liver Safety platform for efficient and fast projects
From human DILI to mechanistic investigations, from cross-species testing to understanding clinical events.
Our Approach to 3D In Vitro Liver Safety
Reliable and fast hazard identification
With 3D InSight™ human liver models, potential drug-induced hepatotoxicity is identified based on 7/14-day treatment and viability readout.
Mechanism of action assessment
Discover mitigation routes by understanding the mechanism of action of in vitro hepatotoxicity through transcriptomics and causality assays.
Cross-species events
Preemptively identify safety hazards in different species to accelerate your pre-clinical process.
Address idiosyncratic clinical events
Our Metaheps™ technology allows us to build liver-like in vitro models from a patient’s blood sample.
