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3D InSight™ Liver Safety Platform
Your proven end-to-end solution portfolio, from reliable hazard identification to insights into translational and clinical toxicology
InSphero’s 3D InSight™ Liver Safety solutions deliver precise and predictive models for assessing liver safety since 2013. Our 3D liver technology accurately models the intricate architecture and functions of the human liver with a physiologically relevant microenvironment to enable better assessments of drug metabolism and toxicological responses. You will gain valuable insights into the mechanisms of drug-induced liver injury by incorporating our 3D InSight™ Liver Safety solutions into your workflow.
Why Liver Safety with InSphero?
InSphero’s 3D InSight Liver Safety Platform has been developed with the needs of a safety toxicologist in mind: biological and physiological relevance, short turn-around times, capable of handling larger compound sets when needed, and the reproducibility you need to make the right decisions.
Market-leading 3D in vitro biology you can rely on
The only spheroid system containing all liver cells, both parenchymal and non-parenchymal.
Trusted by pharmaceutical companies worldwide
Your team will value safety data backed by thousands of compound tests.
Comprehensive solution platform makes your projects efficient and fast
From human DILI to mechanistic investigations, from cross-species testing to understanding clinical events.
Our Approach
Reliable and fast hazard identification
With 3D InSight™ Models, potential hazards are identified based on 7/14-day treatment and viability readout.
Mechanism of action assessment
Discover mitigation routes by understanding the mechanism of action through transcriptomics and causality assays.
Cross-species events
Preemptively identify safety hazards in different species to accelerate your pre-clinical process.
Address idiosyncratic clinical events
Our Metaheps™ technology allows us to build liver-like in vitro models from a patient’s blood sample.
