3D InSight™ Liver Safety Platform

Your proven end-to-end solution portfolio, from reliable hazard identification to insights into translational and clinical toxicology

InSphero’s 3D InSight™ Liver Safety solutions deliver precise and predictive models for assessing liver safety since 2013. Our 3D liver technology accurately models the intricate architecture and functions of the human liver with a physiologically relevant microenvironment to enable better assessments of drug metabolism and toxicological responses. You will gain valuable insights into the mechanisms of drug-induced liver injury by incorporating our 3D InSight™ Liver Safety solutions into your workflow.

Why Liver Safety with InSphero?

InSphero’s 3D InSight Liver Safety Platform has been developed with the needs of a safety toxicologist in mind: biological and physiological relevance, short turn-around times, capable of handling larger compound sets when needed, and the reproducibility you need to make the right decisions.

Market-leading 3D in vitro biology you can rely on

The only spheroid system containing all liver cells, both parenchymal and non-parenchymal.

Trusted by pharmaceutical companies worldwide

Your team will value safety data backed by thousands of compound tests.

Comprehensive solution platform makes your projects efficient and fast

From human DILI to mechanistic investigations, from cross-species testing to understanding clinical events.

Your Success is Our Mission

Schedule a consultation with our experts

Our Approach

Reliable and fast hazard identification

With 3D InSight™ Models, potential hazards are identified based on 7/14-day treatment and viability readout.

Mechanism of action assessment

Discover mitigation routes by understanding the mechanism of action through transcriptomics and causality assays.

Cross-species events

Preemptively identify safety hazards in different species to accelerate your pre-clinical process.

Address idiosyncratic clinical events

Our Metaheps™ technology allows us to build liver-like in vitro models from a patient’s blood sample.


3D InSight™ Predictive Toxicology Service
3D InSight™ Investigative Liver Safety Services
MetaHeps® for Clinical Safety


3D InSight™ Human Liver Microtissues
Akura™ 3D SureKit
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