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3D InSight™ Predictive Toxicology Service
Combining market-leading DILI prediction using our 3D InSight™ Liver Microtissues with fast turnaround time and data quality you can rely on.
Are you facing testing challenges with limited predictability and/or relevance of conventional (often 2D) in vitro models for drug-induced liver injury (DILI)? Do you struggle with accurately simulating complex drug metabolism and toxicological interactions in a controlled laboratory setting?
Our 3D InSight™ Human Liver Microtissues replicate the architecture and functionality of the liver tissue in a 3D spheroid format. We carefully select primary hepatocytes from ten donors and co-culture them with non-parenchymal liver cells, modelling both the parenchymal and non-parenchymal liver functions. Experience the fastest and most convenient access to microtissue technology with our 7- and 14-day 3D InSight™ DILI Service. Simply ship your compounds to us and receive a comprehensive analysis report based on our market-leading expertise in 3D liver toxicology.
Why DILI with InSphero?
We inspire researchers, worldwide, to reach their full potential so that life changing therapies can ultimately make it into the hands of patients.
Market-leading 3D in vitro biology you can rely on
The only spheroid system containing all liver cells, both parenchymal and non-parenchymal.
Trusted by pharmaceutical companies worldwide
Your team will value safety data backed by thousands of compound tests.
Fast turnaround to accelerate your projects
Our streamlined, automated, and 3D-optimized workflow guarantees reliable data in record time.
Seamless transition to investigative, mechanistic assays when needed
Flagged a DILI concern? Our team takes your compound directly to mechanistic assays in no time to decipher the mechanisms of toxicity of your compound.
Our Process
Select from our easy-to-navigate solutions
From basic DILI hazard identification to multi-parametric readouts, we have the right solution for you.
Convenient compound shipping
Send your compounds to us. We'll monitor the shipment while the 3D liver microtissues are in preparation.
We run the assay
Multiple dosings, optimized read-outs, all done using our streamlined process.
Impress with our comprehensive report
Our report gives you everything you need to present the results to your organization.
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