3D InSight™ Predictive Toxicology Service | 3D In Vitro DILI Testing

Combining market-leading 3D in vitro DILI prediction using our
3D InSight™ Liver Microtissues with fast turnaround time and data quality you can rely on.

Industry-ready 3D In Vitro DILI Testing

Are you facing testing challenges with limited predictability and/or relevance of conventional (often 2D) in vitro models for drug-induced liver injury (DILI)? Do you struggle with accurately simulating complex drug metabolism and toxicological interactions in a controlled laboratory setting?

Experience the fastest and most convenient 7- and 14-day 3D in vitro DILI testing with our 3D InSight™ services. InSphero's predictive toxicology expertise is based on the 3D InSight™ Human Liver Microtissues, which replicate the architecture and functionality of the liver tissue in a 3D spheroid format. We carefully select primary hepatocytes from ten donors and co-culture them with non-parenchymal liver cells, modeling both the parenchymal and non-parenchymal liver functions.

Simply ship your compounds to us and receive a comprehensive analysis report based on our market-leading expertise in 3D In Vitro Liver Safety.

Why 3D In Vitro DILI with InSphero?

We enable liver safety researchers to reach the full potential of 3D in vitro DILI testing through scalable, reliable and reproducible 3D human models and advanced scientific expertise.

An icon demonstrating the market-leading 3D in vitro liver toxicology solutions by InSphero

Market-leading 3D in vitro biology you can rely on

The only 3D in vitro human liver model containing all liver cells, both parenchymal and non-parenchymal, reflecting reliably the complex biology of the human liver.

An icon showcasing the 3D in vitro liver safety platform trusted by pharmaceutical companies worldwide. 3D in vitro DILI testing used by the top ten pharmaceutical companies.

3D in vitro DILI trusted by pharma companies worldwide

Your team will value safety data backed by thousands of compound tests performed in our robust 3D InSight™ Human Liver Microtissues.

An icon demonstrating InSphero's 3D in vitro human liver model which enables fast and efficient safety assessment projects

Fast turnaround to accelerate your projects

Our streamlined, automated, and 3D-optimized workflow guarantees reliable data in record time.

Seamless transition to investigative, mechanistic assays when needed

Flagged a DILI concern? Our team takes your compound directly to mechanistic assays in no time to decipher the mechanisms of toxicity of your compound.

Your Success is Our Mission

Schedule a consultation with our experts

Our 3D In Vitro DILI Process

Select from our easy-to-navigate solutions

From basic DILI hazard identification to multi-parametric readouts, we have the right solution for you.

Convenient compound shipping

Send your compounds to us. We'll monitor the shipment while the 3D liver microtissues are in preparation.

Our 3D in vitro experts run the assay

Multiple dosings, optimized read-outs, all done using our streamlined process.

Impress with our comprehensive report

Our report gives you everything you need to present the results to your organization.

Featured resources

How to Evaluate Preclinical and Clinical DILI
Expression Analysis of Exosomal MicroRNAs in Chlorpromazine Treated Human Hepatic Spheroids: A Promising Tool for Novel Drug-Induced Liver Injury Biomarker Discovery
3D InSight™ Liver Platform - DILI Service Overview

Related products

3D InSight™ Human Liver Microtissues
Akura™ 3D SureKit
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