Blog - InSphero
April 16, 2021
Vitruvian Rat and Man

Measuring Aspartate Transaminase (AST) In Vitro – Closing the Gap to Clinical Data

InSphero's Scientific Ambassador Sue Grepper PhD highlights how to recapitulate clinically observed increase of aspartate aminotransferase (AST) levels in preclinical in vitro safety studies. If you have experienced a clinical […]
November 27, 2020
Season's Greetings

2020 Year In Review: Rising to New Challenges

InSphero CEO Jan Lichtenberg extends holiday greetings from our teams in Switzerland and the United States, and looks back on the highlights of 2020: a tumultuous year shaped by a […]
November 26, 2020

Shipping Live Mini-Organs Around the World

InSphero Head of Operations David Fluri explains how our new award-winning InFloat™ shipping system helps make 3D in vitro cell technology more accessible to researchers worldwide. Did you know that […]
September 6, 2020

Understanding the Power of Islet Standardization for Diabetes Research

InSphero Scientist and islet biologist Joan Mir Coll discusses how multiparametic approaches for in vitro pancreatic research have the potential to revolutionize diabetes research. Over the past 3 decades, diabetes […]
July 2, 2020
Organ on a chip system for Diabetes Drug Discovery

A Novel Hanging Drop Organ-on-a-Chip System for Diabetes Drug Discovery

InSphero has a rich history of collaborating with researchers at ETH Zürich. The most recent example is a joint effort to develop and apply a novel microfluidic perifusion system to […]
June 12, 2020
Akura Flow technology

Understanding Microfluidics: Toward Scalable
Body-on-a-Chip Systems

Microfluidics expert Olivier Frey explains how higher-order systems, such as multi-tissue Body-on-a-Chip networks, have the potential to faithfully replicate physiological interactions among different human organs–and what hurdles remain before this […]
May 1, 2020
Live-cell imaging of immune cell infiltration in a 3D lung carcinoma model:

The Future of High Content Analysis is 3D

InSphero recently had an opportunity to test the Yokogawa Platform for High Content Analysis (HCA) in our laboratories in Schlieren, Switzerland. Our goal was to see whether the Yokogawa instrument […]
May 1, 2020
NASH model treatments

Experimental Design Considerations for
NASH Drug Screening

An ongoing challenge in NASH Drug Discovery is selecting “fit for purpose” models for preclinical drug screening. InSphero liver expert Sue Grepper and Head of Liver Solutions Eva Thoma recently […]
March 13, 2020
InSphero Live Webinar

InSphero launches new webinar series, starting with virtual SOT 2020 sessions

As the coronavirus epidemic prompts cancellations of scientific meetings around the world, we have been working on alternative methods to keep you informed of advances in 3D cell-based assay technology, […]
February 26, 2020
CAR-T Attack

Are I-O therapeutics making traditional in vitro assays obsolete?

InSphero Oncology Experts Francesca Chiovaro and Irina Agarkova often collaborate closely with academic and pharma partners who are developing therapeutics that target the innate immune system. In this blog, Francesca shares […]