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- Poster
- Oncology & Immunology
Scalable and Reproducible 3D Tumor Spheroid Models for Assessing Therapeutic Antibody Penetration and Efficacy
- Webinar
- Oncology & Immunology
Accelerate Your Oncology Research Through Assay-Ready Cryopreserved Tumor Tissues
- Poster
- Liver Disease
Screening and comparison of current clinical candidates and various modalities in MASH using human liver spheroids
- Poster
- Liver Safety
Species-specific Liver Microtissues: A Set Of Microphysiological Systems To Assess Translational Hepatotoxicity In Drug Development
- Poster
- Oncology & Immunology
A Novel Microplate Format for Tumor Cell Cryopreservation and 3D Tumor Spheroids Formation to Streamline Pre-clinical Drug Testing
- Poster
- Islet Biology
Hide and Seek- Protecting Human β-cells in T1D by modulating their PDL1 and HLA Class I expression
- Poster
- Islet Biology
AAV Capsid Variant Screen for Diabetes Research: Building a high-throughput compatible methodology for modification of human islet gene expression
- Publication
- Liver Safety
InSphero & FDA's NCTR Peer-reviewed Paper | Physiological liver microtissue 384-well microplate system for preclinical hepatotoxicity assessment of therapeutic small molecule drugs
- Video
- 3D Cell Culture Technology
InSphero’s Mission to Reduce Animal Testing in Drug Discovery - an Interview with LSCV
- Poster
- Liver Safety
Early Detection of Hepatotoxic Compounds in Drug Development: Leveraging the Potential of Human Liver Microtissues for Predictive Screening
- Application Note
- 3D Cell Culture Technology
Automated Tumor Spheroid Handling on the epMotion® 5073t using InSphero Akura™ Plates
- Publication
- Liver Disease
Digital pathology with artificial intelligence analysis provides insight to the efficacy of anti-fibrotic compounds in human 3D MASH model
- Poster
- 3D Cell Culture Technology
Assessment of cancer metastatic potential in Akuraâ„¢ Immune Flow Platform
- Webinar
- 3D Cell Culture Technology, Liver Safety
The 3D DILI Model of Success – from Biological Relevance to Industry Application
- Poster
- 3D Cell Culture Technology, Liver Disease
Scalable 3D Cell Culture-based Retinal Fibrosis Model for Efficacy Testing
- Poster
- Oncology & Immunology
Assess the effects of tumor-dendritic cell reprogramming, using the 3D InSightâ„¢ Oncology and Immunology Platform
- Webinar
- 3D Cell Culture Technology, Oncology & Immunology
Advancing Oncology and Immune-Oncology Therapeutic Development Using 3D Tumor Spheroids
- Poster
- Liver Disease
Digital pathology with artificial intelligence analysis provides insight to the efficacy of anti-fibrotic compounds in human 3D MASH model
- Poster
- 3D Cell Culture Technology
Extending the choice of ULA plates for primary 3D human liver spheroid formation and experimentation with the Akuraâ„¢ Spheroid Microplates
- Poster
- 3D Cell Culture Technology
Deciphering Metabolic Cross-Talk: Insights into Liver-Islet Interactions with human Microtissues and scalable Microphysiological Systems
- Application Note
- 3D Cell Culture Technology
Enhancing Scalability and Quality of 3D In Vitro Cell Models Production through Automation
- Poster
- 3D Cell Culture Technology, Oncology & Immunology
Assessment of immune cell infiltration and cancer metastatic potential in Akuraâ„¢ Immune Flow Chip - A microfluidic 3D spheroid system
- Brochure
- Oncology & Immunology
3D InSightâ„¢ Tumor Spheroids: Balancing Physiological Relevance with Scalability and Reliability in Oncology Therapeutic Testing
- Brochure
- Oncology & Immunology
Human 3D InSightâ„¢ Tumor Spheroids: Reliable and Scalable In Vitro System to Model Immune Responses and Evaluate Cancer Immunotherapeutics
- Brochure
- Oncology & Immunology
Innovation in 3D In Vitro Oncology: Novel Insights and Reproducible Results with Data-Driven ADC Penetration Study
- Poster
- Oncology & Immunology
New microplate platform with cryopreserved 3D tumor spheroids for faster and convenient pre-clinical testing
- Poster
- 3D Cell Culture Technology, Liver Safety, Oncology & Immunology
Mitigation of liver toxicity effects of bispecific T cell engagers in immune-competent liver-tumor co-culturing high-throughput platform
- Poster
- Liver Safety
Initial evaluation of the use of human liver microtissues for the hepatotoxicity assessment of antisense oligonucleotides
- Poster
- Liver Disease
Patient-derived steatotic hepatocytes reveal non-cell autonomous inflammation and fibrogenic effects in multicellular liver spheroids
- Video
- 3D Cell Culture Technology, Oncology & Immunology
ARCTisâ„¢ Cryo Tissues - How to prepare plate
- Publication
- Liver Safety
Preclinical Characterization and Phase I Trial Results of INBRX-109, A Third-Generation, Recombinant, Humanized, Death Receptor 5 Agonist Antibody, in Chondrosarcoma
- Webinar
- 3D Cell Culture Technology, Oncology & Immunology
Predicting Metabolism-Related Drug-Drug Interactions with Organ-on-a-Chip Technology
- Webinar
- 3D Cell Culture Technology
Scalable 3D Cell Culture Technologies Engineered for Physiological InSight
- Webinar
- 3D Cell Culture Technology
Implementing High Resolution, High Content Image Analysis with Multicellular 3D Spheroid Models
- Webinar
- 3D Cell Culture Technology
Optimizing High-Content Imaging of 3D Models for Drug Discovery
- Webinar
- Liver Safety
Optimizing 3D Spheroid Models for Efficient Drug-Induced Liver Injury Screening
- Webinar
- Islet Biology
A Novel, High-Resolution Perifusion Platform for Studying Insulin Release Dynamics of Single Human Pancreatic Islets
- Webinar
- Liver Disease
Redefining NASH Drug Discovery: A New Approach to Complex Disease Modeling
- Webinar
- Liver Disease
Artificial Intelligence in Digital Pathology: Quantification of Fibrosis in Human 3D NASH Model
- Video
- 3D Cell Culture Technology
InSphero and Hamilton collaborate to improve the production and handling of spheroids
- Video
- Islet Biology
3D InSightâ„¢ Human Islet Microtissues as an in vitro and an in vivo model system for Type 1 and Type 2 Diabetes
- Video
- Liver Disease
Human 3D in vitro NASH model for efficacy testing of clinical drug candidates
- Video
- 3D Cell Culture Technology
Manual medium exchange under 2 minutes with InSphero Akuraâ„¢ 96 Spheroid Microplate
- Video
- 3D Cell Culture Technology
InFloatâ„¢ Shipping Solution for 3D InSightâ„¢ Assay-ready Microtissues
- Video
- Liver Disease
How we applied InSphero technology to create a human liver NASH model
- Publication
- 3D Cell Culture Technology
Three-dimensional renal organoids from whole kidney cells: generation, optimization, and potential application in nephrotoxicology in vitro
- Publication
- 3D Cell Culture Technology
Extra Cellular Matrix Deposition and Assembly in Dermis Spheroids
- Publication
- 3D Cell Culture Technology
Generation of uniform liver spheroids from human pluripotent stem cells for imaging-based drug toxicity analysis
- Publication
- 3D Cell Culture Technology
In vitro cell culture of patient derived malignant pleural and peritoneal effusions for personalised drug screening
- Publication
- 3D Cell Culture Technology
Formation and optimization of three-dimensional organoids generated from urine-derived stem cells for renal function in vitro
- Publication
- 3D Cell Culture Technology
miR-149 suppresses breast cancer metastasis by blocking paracrine interactions with macrophages
- Publication
- 3D Cell Culture Technology
Assessing the predictive response of a simple and sensitive blood-based biomarker between estrogen-negative solid tumors
- Publication
- 3D Cell Culture Technology
Activated Cardiac Fibroblasts Control Contraction of Human Fibrotic Cardiac Microtissues by a -Adrenoreceptor-Dependent Mechanism
- Publication
- 3D Cell Culture Technology
Patient-derived tumor spheroid cultures as a promising tool to assist personalized therapeutic decisions in breast cancer
- Publication
- Liver Disease
Particulate and drug-induced toxicity assessed in novel quadruple cell human primary hepatic disease models of steatosis and pre-fibrotic NASH
- Publication
- Liver Disease
A 3D primary human cell-based in vitro model of non-alcoholic steatohepatitis for efficacy testing of clinical drug candidates
- Publication
- 3D Cell Culture Technology
Heterologous Protein Production Capacity of Mammalian Cells in 2D and 3D cultures
- Publication
- 3D Cell Culture Technology
Scaffold-free cell delivery for use in regenerative medicine
- Publication
- 3D Cell Culture Technology
A Novel Concept for Scaffold-Free Vessel Tissue Engineering: Self-Assembly of Microtissue Building Blocks
- Publication
- 3D Cell Culture Technology
Microscale tissue engineering using gravity-enforced cell assembly
- Publication
- 3D Cell Culture Technology
An in vitro osteosarcoma 3D microtissue model for drug development
- Publication
- 3D Cell Culture Technology
Integrating Microtissues in Nanofiber Scaffolds for Regenerative Nanomedicine
- Publication
- 3D Cell Culture Technology
A 3D co-culture microtissue model of the human placenta for nanotoxicity assessment
- Publication
- 3D Cell Culture Technology
A Framework for Optimizing High-Content Imaging of 3D Models for Drug Discovery
- Publication
- Liver Safety
Multi-cell type human liver microtissues for hepatotoxicity testing
- Publication
- Liver Safety
Characterization of a Rat Multi-Cell Type 3D-Liver Microtissue System
- Publication
- Liver Safety
State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology
- Publication
- Liver Safety
Differential basolateral-apical distribution of scavenger receptor, class B, type I in cultured cells and the liver
- Publication
- Liver Safety
Hepatic toxicology following single and multiple exposure of nanomaterials utilising a novel primary human 3D liver microtissue model
- Publication
- Liver Safety
Extending the limits of quantitative proteome profiling with data-independent acquisition and application to acetaminophen treated 3D liver microtissues
- Publication
- 3D Cell Culture Technology, Oncology & Immunology
A High-Throughput–Compatible 3D Microtissue Co-culture System for Phenotypic RNAi Screening Applications
- Publication
- 3D Cell Culture Technology, Oncology & Immunology
3D cell culture systems modeling tumor growth determinants in cancer target discovery
- Publication
- 3D Cell Culture Technology, Oncology & Immunology
Development of an innovative 3D cell culture system to study tumour–stroma interactions in non-small cell lung cancer cells
- Publication
- 3D Cell Culture Technology, Oncology & Immunology
Additive impact of HER2-/PTK6-RNAi on interactions with HER3 or IGF-1R leads to reduced breast cancer progression in vivo
- Publication
- 3D Cell Culture Technology, Oncology & Immunology
A 3D-microtissue-based phenotypic screening of radiation resistant tumor cells with synchronized chemotherapeutic treatment
- Publication
- 3D Cell Culture Technology, Oncology & Immunology
Three-dimensional microtissues essentially contribute to preclinical validations of therapeutic targets in breast cancer
- Publication
- 3D Cell Culture Technology, Oncology & Immunology
Evaluation of assays for drug efficacy in a three-dimensional model of the lung
- Publication
- Liver Safety
Hepatic 3D spheroid models for the detection and study of compounds with cholestatic liability
- Publication
- Liver Safety
Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072
- Publication
- Liver Safety