Scalable 3D Cell Culture Technologies Engineered for Physiological InSight

Over the past decade, 3D spheroids have become the model of choice for many drug discovery applications due to their physiologically relevant morphological characteristics, cellular complexity, and longevity in culture.

Spheroids can now be engineered to mimic many human tissues and organs, ranging from simple tumor models derived from well-established cancer cell lines to complex triple-culture liver models produced from primary human donor cells. Increasingly, these 3D models have also been adapted for use in assay- and automation-ready plate formats, including 96- and 384-well plates, as well as emerging microfluidic systems that support organ networks.

In this webinar, InSphero Vice President of Technologies and Platforms, Dr. Olivier Frey, and Senior Product Manager Dr. Frauke Greve, give an in-depth introduction to the 3D cell-culture technology underlying all InSphero platforms and services and share how our partners in academia and industry have helped us push the boundaries of what’s possible with 3D in vitro modeling today.

You will learn:

  • How InSphero has engineered and optimized scalable, automation-friendly microplate technology for production and handling of complex multicellular 3D spheroid models that address the drug discovery needs of researchers, whether they want to use our models in-house for routine screening or engage InSphero as a discovery partner.
  • The basics of biomicrofluidic devices that make plug-and-play organ-on-a-chip solutions more accessible and affordable for life science research teams
  • Challenges of shipping live 3D cell cultures and the unique solution our team developed to ensure plates of microtissues always arrive upright and ready to assay
  • Tips for choosing the most appropriate plates and 3D spheroid models for common biopharma applications, such as high throughput compound screening and high content imaging and analysis
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