ARCTis™ Human Tumor - Cryopreserved 3D Tumor Models for
In Vitro Oncology Research
Enter a New Dimension of Drug Discovery with ARCTis™ - Always Ready Cryo Tissue for Cancer Drug Discovery
ARCTis™ - cryopreserved 3D tumor models
InSphero ARCTis™ ("Always Ready Cryo Tissues") is an innovative 3D cell culture technology that enables lead compounds testing with human-derived 3D tumor models, cryopreserved in spheroid microplates. Conveniently stored at - 80 °C in your freezer, the plates with cryo tissues are always available, so you can start an experiment without delays due to logistics or production time.
Instead of investing time and resources in culturing spheroids, simply take an ARCTis™ plate from the freezer and follow our protocols for convenient and fast scaffold-free formation of uniform spheroids. Our current portfolio encompasses 20 of the most commonly used human cancer cell lines. This means that you can easily study the effect of your compounds on a broad range of tumor models.
Discover ARCTis™ for 3D in vitro cancer research
InSphero's reproducible, reliable and scalable cryopreserved 3D tumor models upscale your 3D in vitro oncology research. Advance your drug discovery experiments through our industry-validated 3D cell culture technology:
- Based on Akura™ microplate technology with SureXchange™ ledge (no spheroid loss during medium exchange)
- Standardized human tumor spheroids, enabling reliable results
- Ease of mind through certified production with cell line identification based on STR profiling, as well as virus and mycoplasma testing
ARCTis™ - A Game Changer in 3D Cancer Research
The platform allows you to use 3D cell culture for lead testing in a fast and simple manner. This sets the focus on data generation from functionally relevant tumor models. A quick and convenient process for successful lead characterization.
50% Lower Assay Costs
ARCTis™ Human Tumor models are optimized for reliable formation, uniform size, cell composition, and growth window.
80% Faster Assay Start
From freezer to assay-ready 3D tumor spheroids in 72h, so you and your team get a head start in project execution.
Broad Range of 3D Tumor Models
20 cell lines at present - and growing. We are building the largest cryopreserved human 3D tumor models bank in the world: monotypic and co-cultures.
100% Reliability
Uniform tumor spheroids in every well, unmet plate-to-plate and batch-to-batch repeatability, guaranteed cell line identity.
ARCTis™ Cryopreserved 3D Tumor Models
Concept & Workflow
Long-term Storage
Conveniently stored at -80°C freezer with months-long shelf life
Thawing
Simple 30 min thawing protocol followed by tissue regeneration within 3-5 days in incubator
Experiment
Run your assay the same way as with fresh 3D tumor models
Data Analysis
Collect reliable and reproducible data for early-stage decision-making
Cryopreserved 3D Tumor Models | Available Cancer Cell Lines
Available Cell Lines for Brain tissue:
- HMC3
- U-87 MG
Available Cell Lines for Breast tissue:
- T47D
Available Cell Lines for Cervix tissue:
- HeLa - Please note, HeLa is often seen as a screening reference and less as a disease model
Available Cell Lines for Colon tissue:
- DLD-1
- HCT116
- HCT15
- HT29
Available Cell Lines for Connective tissue:
- HT-1080
Available Cell Lines for Kidney tissue:
- A498
Available Cell Lines for Liver tissue:
- HepG2
Available Cell Lines for Lung tissue:
- A549
- NCI-H1299
- NCI-H1975
- NCI-H460
- NCI-H2170
Available Cell Lines for Ovary tissue:
- SK-OV-3
Available Cell Lines for Pancreas tissue:
- Panc-1
Available Cell Lines for Skin tissue:
- A375
Looking for additional cell lines or interested in having ARCTis™ plates generated from your own tumor models? Contact us today!
ARCTis™ Human Tumor Platform
