InSphero at the European Islet Study Group 2025
Join us at the European Islet Study Group 2025 in Malmö, Sweden, where we’ll showcase how our Akura™ platforms and 3D in vitro models are advancing diabetes research. Learn how our solutions support deeper insights into islet biology, β-cell function, and therapeutic development.
Explore all our activities taking place during European Islet Study Group 2025 in Malmö from Wednesday, June 11 to Friday, June 13. See you there!
Meet our Team at the ADA 2025


Burcak Yesildag, PhD
Vice President, Islet Biology
Burcak Yesildag, PhD
Vice President, Islet Biology
Burcak Yesildag obtained her master’s degree in Biochemistry and her PhD degree in Translational Biomedicine from ETH Zurich, where she specialized in pancreatic islet biology. In 2015, Dr. Yesildag joined the InSphero team to establish the company as a strong contender in the field of diabetes research. Her team is facilitating the adoption of InSphero’s innovative platforms, based on primary or stem-cell derived human cells, by a broad scientific community around the world, aiming to support translation of new discoveries into much needed therapeutic interventions.




Alexandra Title, PhD
Vice President, Islet Biology
Alexandra Title, PhD
Vice President, Islet Biology
Alexandra Title is VP of Islet Biology at InSphero. Her work focuses on developing physiologically relevant, scalable human islet models of type 1 and type 2 diabetes to support target validation and therapeutic drug testing. Alexandra holds a PhD in molecular and translational biomedicine from ETH Zurich, during which she worked with mouse models of beta-cell tumors and diabetes. Prior to her role as VP, she worked as a senior scientist on the Islet Biology team at InSphero for 4.5 years.




Lynn Scherpe
Research Associate
Lynn Scherpe
Research Associate
Lynn Scherpe holds a Bachelor's degree in Biology from Maastricht University and a Master's degree in Molecular Health Sciences from ETH Zurich. In early 2024, she joined the Islet Biology team as a Research Associate, supporting projects in diabetes research and pre-clinical toxicology. Her current work is primarily concerned with type 1 diabetes (T1D)-oriented service projects, aimed at identifying and developing novel therapeutic strategies for T1D. She specializes in co-culturing islet microtissues with immune cells to create physiologically relevant T1D models, which serve as a platform for the pre-clinical evaluation of immunotherapies.




Christine Schwenk
Business Development Manager
Christine Schwenk
Business Development Manager
With a BSc and MSc degree in Medical Biotechnology from Berlin, Germany, Christine began her career as a Scientist specializing in 3D in vitro cell culture and organ-on-chip systems. Transitioning into Business Development in 2020, she has since focused on driving collaborations betweem CROs and Industry for early drug discovery. Currently serving as the Business Development Manager for Nordics & UK at InSphero AG since August 2023, Christine is passionate about advancing preclinical 3D cell culture solutions and Multi-Organ-Chips for drug safety and efficacy testing. Her work is dedicated to improving the drug development processes, fostering innovation, and reducing reliance on animal testing to enhance faster development of new treatment options for patients.


Posters at the European Islet Study Group 2025
Modelling Alpha-Cell Dysfunction in T1D with Reaggregated Primary Human Islet and Proinsulin-Specific Cytotoxic T Lymphocyte Co-Cultures
Date: Wednesday, June 11th | 17:45
Poster board number: 201


Alexandra Title, PhD
Vice President, Islet Biology
Alexandra Title, PhD
Vice President, Islet Biology
Alexandra Title is VP of Islet Biology at InSphero. Her work focuses on developing physiologically relevant, scalable human islet models of type 1 and type 2 diabetes to support target validation and therapeutic drug testing. Alexandra holds a PhD in molecular and translational biomedicine from ETH Zurich, during which she worked with mouse models of beta-cell tumors and diabetes. Prior to her role as VP, she worked as a senior scientist on the Islet Biology team at InSphero for 4.5 years.


Hide and seek: Protecting human β-cells in T1D by modulating their PDL1 and HLA Class I expression
Date: Wednesday, June 11th | 17:45
Poster board number: 220


Lynn Scherpe
Research Associate
Lynn Scherpe
Research Associate
Lynn Scherpe holds a Bachelor's degree in Biology from Maastricht University and a Master's degree in Molecular Health Sciences from ETH Zurich. In early 2024, she joined the Islet Biology team as a Research Associate, supporting projects in diabetes research and pre-clinical toxicology. Her current work is primarily concerned with type 1 diabetes (T1D)-oriented service projects, aimed at identifying and developing novel therapeutic strategies for T1D. She specializes in co-culturing islet microtissues with immune cells to create physiologically relevant T1D models, which serve as a platform for the pre-clinical evaluation of immunotherapies.


Adeno-associated virus capsid variant screen for diabetes research: building a scalable methodology for modification of gene expression in primary human islets
Date: Thursday, June 12th | 17:30
Poster board number: 323
