In the first part of the webinar, Bruno Filippi, Vice President of Liver Safety, introduces 3D InSight™ Liver Microtissues, advanced in vitro models designed to assess the safety of drug candidates prior to first-in-human studies. He will explain how these microtissues are used to uncover mechanisms of toxicity and improve preclinical decision-making.
In the second part, Piyush Bajaj, Distinguished Scientist at Sanofi, presents a real-world case study demonstrating how liver microtissues were applied to de-risk a liver finding observed in dogs treated with the selective estrogen receptor degrader Amcenestrant.
