SOT 2025

InSphero at the SOT 2025

Join us at the SOT 2025 in Orlando, Florida. This premier event for toxicology professionals is the perfect opportunity to explore the latest advancements in the field. Visit our booth #1211 to discover how our innovative solutions transform toxicological research and drive safety and sustainability progress.

Don’t miss out on all the exciting activities we’ve planned during SOT 2025, happening from Sunday, March 16, to Thursday, March 20. We can’t wait to connect with you there!

Meet our Team at the SOT 2025

Jan Lichtenberg

Jan Lichtenberg, PhD

CEO and Co-Founder
Madhu Nag

Madhu Nag, PhD

Chief Scientific Officer
Bruno Filippi

Bruno Filippi, PhD

Vice President, Liver Safety

Arumugham (Ragoo) Raghunathan, PhD

Senior Director Business Development

Arnab China, PhD

Business Development Manager

Our Booth at the SOT 2025

Visit our booth #1211 and discover our 3D InSight™ Liver Safety - Practical, Physiological & Cost-effective 3D In Vitro Solutions for DILI Assessment

Poster at the SOT 2025

Physiological liver microtissue 384-well microplate system for preclinical hepatotoxicity assessment of therapeutic small molecule drugs

Date: Monday, 17 March, 2025 | 9:15 - 11:45 AM

Poster number: 3264

Bruno Filippi

Bruno Filippi, PhD

Vice President, Liver Safety

Exhibitor-Hosted Session at the SOT 2025

The 3D InSightâ„¢ Liver Microtissues Platform: a Versatile Tool for In Vitro Hepatotoxicity Studies

Date: Wednesday, 19 March, 2025 | 12:15 - 1:15 PM

Location: W208A

The 3D InSightâ„¢ Liver Microtissue technology enables the large-scale production of miniaturized and standardized liver spheroids made of primary hepatocytes and non-parenchymal liver cells. The 3D InSightâ„¢ Liver Microtissue is a versatile micro-physiological liver system to perform hepatotoxicity studies during the entire drug discovery and development process, from initial screenings of large compound sets to detailed investigations aiming at uncovering mechanisms of toxicity. The utility of liver microtissues in the drug development process will also be exemplified by Piyush Bajaj, distinguished scientist working in the investigative toxicology department at Sanofi, in a presentation on how liver microtissues played a key role in the derisking of Amcenestrant, an investigational oral selective estrogen receptor degrader currently being evaluated for the treatment of breast cancer.

Bruno Filippi

Bruno Filippi, PhD

Vice President, Liver Safety

SOT 2025 Resources

3D InSightâ„¢ | 3D In Vitro Liver Toxicology Services
3D InSightâ„¢ Translational Toxicology Services
3D InSightâ„¢ Human Liver Microtissues
Species-specific Liver Microtissues: A Set Of Microphysiological Systems To Assess Translational Hepatotoxicity In Drug Development
Early Detection of Hepatotoxic Compounds in Drug Development: Leveraging the Potential of Human Liver Microtissues for Predictive Screening
Mitigation of liver toxicity effects of bispecific T cell engagers in immune-competent liver-tumor co-culturing high-throughput platform
Initial evaluation of the use of human liver microtissues for the hepatotoxicity assessment of antisense oligonucleotides
Akuraâ„¢ 3D SureKit - New All-in-one Kit for 3D Liver Microtissue Formation
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