3D InSight™ Investigative Toxicology | 3D In Vitro Liver Safety Services

Fast and reliable identification of mechanisms of toxicology based on the market-leading human 3D Liver Safety platform

Industry-ready 3D In Vitro Investigative Toxicology

InSphero’s Investigative Toxicology services offer a comprehensive set of solutions to decipher the mechanism of toxicity of a substance. Profiling and hypothesis generation are supported by state-of-the art ‘omics technology, while a comprehensive portfolio of biomarker analysis and classical toxicology mechanistic assays can test a broad set of toxic reactions. InSphero’s team supports you in identifying potential hepatotoxic substances and understanding their mechanisms of toxicity to guide your risk assessment with confidence within weeks.

Why Investigative Toxicology with InSphero?

We help toxicologists, worldwide, to understand the mechanism of action of liver toxicity through an in-depth analysis based on the advanced 3D InSight™ Human Liver Microtissues.
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Market-leading 3D in vitro biology you can rely on

Finding answers to complex questions requires a model faithfully modeling liver biology. InSphero’s spheroid system containing all liver cells, both parenchymal and non-parenchymal, delivers.

We seamlessly go from hazard identification to investigative toxicology

By using our 7 or 14-day DILI service to identify an issue, you can proceed to an investigative study in no time.

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Fast turnaround to accelerate your projects

Our streamlined, automated, and 3D-optimized workflow guarantees reliable data in record time.
An icon showcasing the 3D in vitro liver safety platform trusted by pharmaceutical companies worldwide. 3D in vitro DILI testing used by the top ten pharmaceutical companies.

Trusted by pharmaceutical companies worldwide

Your team will appreciate safety data that has been proven by thousands of compound tests.

3D In Vitro Investigative Toxicology Assays

  • Glutathione Causality
  • CYP450 causality
  • Inflammation causality
  • Bile Acid Causality
  • Bile acid secretion
  • Canalicular secretion
  • Cytokine secretion
  • Mitochondrial function
  • Low-input Bulk RNA transcriptomic
  • TempO-Seq RNA transcriptomic

Your Success is Our Mission

Schedule a consultation with our experts

Our Investigative Toxicology Process

Expert project planning

Our 3D in vitro liver safety experts develop a concise plan to identify the underlying mechanism of toxicity.

Executing the action plan

We know your request is urgent. Our team will execute the action plan swiftly and update you on the progress.

Expert review by experienced liver toxicology scientists

We know your request is urgent. Our team will execute the action plan swiftly and update you on the progress.

Impress with a comprehensive report

We know your request is urgent. Our team will execute the action plan swiftly and update you on the progress.

Featured resources

A Novel Framework for Teasing Out Mechanisms of DILI
3D InSight™ Liver Platform - Investigative toxicology

Related products

3D InSight™ Human Liver Microtissues
Akura™ 3D SureKit
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