3D InSight™ | 3D In Vitro Liver Disease

Imagine the complex nature of liver disease biology condensed into a few plates of assay-ready 3D microtissues. InSphero's 3D in vitro liver disease platform provides you with data and insights that exponentially accelerate your research in MASH (NASH) and MASLD (NAFLD) drug discovery.

Industry-ready 3D In Vitro Liver Disease Solutions

Benefit from our market-leading 3D in vitro human models for liver disease drug discovery. Our controlled, scalable, biologically relevant, and cost-effective screening platform for MASH and MASLD unlocks the full potential of your research.

The 3D InSight™ Human Liver Microtissues facilitate studies of disease mechanisms, enable early assessment of drug safety and efficacy, and accurately simulate human liver pathology. InSphero's 3D in vitro liver disease platform:

Enhances your ability to predict human responses
Reduces the chances of late-stage clinical failures
Expedites the drug discovery process
Preserves valuable resources for your team

Why 3D In Vitro Liver Disease with InSphero?

InSphero’s 3D In Vitro Liver Disease Platform reflects the needs of liver drug discovery researchers: high physiological relevance, uniformity, scalability, which bring your MASH and MASLD research to the next level.

Based on the 3D in vitro human liver gold standard

InSphero has pioneered the gold standard for liver toxicology with its 3D InSight™ Liver Model. Based on it, our disease models are leveraging the uniformity, robustness, and ease of use that accelerates your research.

Unique pairs of diseased and healthy 3D microtissues

We create twins of diseased and healthy 3D microtissues of the same genetic origin, providing you with high-quality Next-Generation Sequencing (NGS) data that was previously unattainable.

Scalable & automation-friendly 3D in vitro liver disease platform

Whether starting from scratch or repurposing, our liver discovery platform is the only one on the market that enables automated screening.

3D In Vitro MASH Screening for Lead Selection
Starting in April 2026

Benefit our scalable, reliable, and reproducible 3D Liver MASH Model for:

Cost-effective identification and prioritization of promising MASH candidates
De-risked go / no-go decisions through multiparametric analysis of key MASH hallmarks

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Our Approach to 3D In Vitro Liver Disease

In-depth requirement analysis

Our expert team has supported hundreds of research groups in 3D cell culture. We invest efforts to understand your goals and requirements, so we can deliver fast and high-quality results.

Project proposal

Whether you use our products in-house or partner with us to utilize our 3D in vitro liver disease services, you receive a comprehensive proposal to outline the research project.

Execution to success

Time and quality matter - and we guarantee both when partnering with you. You can rely on our expertise, excellent processes, and dedication to your success.

Impress with a comprehensive report

Our detailed report gives you everything you need to present the results to your organization.

3D InSight™ | 3D In Vitro Liver Disease

Industry-ready 3D In Vitro Liver Disease Solutions